Alveolar epithelial cells of lung fibrosis patients are susceptible to severe virus-induced injury
- Creator: Read, Jane , Reid, Andrew T. , Schuliga, Michael , Thomson, Claire , Plit, Marshall , Mejia, Ross , Knight, Darryl A. , Lize, Muriel , Kasmi, Karim E. , Grainge, Christopher , Stahl, Heiko
- Resource Type: journal article
- Date: 2024
Mechanical forces suppress antiviral innate immune responses from asthmatic airway epithelial cells following rhinovirus infection
- Creator: Veerati, Punnam Chander , Reid, Andrew T. , Nichol, Kristy S. , Wark, Peter A. B. , Knight, Darryl A. , Bartlett, Nathan W. , Grainge, Christopher L.
- Resource Type: journal article
- Date: 2023
Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap
- Creator: Tu, Xiaofan , Kim, Richard Y. , Loering, Svenja , Nguyen, Duc H. , Nair, Prema Mono , Haw, Tatt Jhong , Alemao, Charlotte A. , Faiz, Alen , Tay, Hock L. , Wark, Peter A. B. , Knight, Darryl A. , Foster, Paul S. , Brown, Alexandra C. , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip M. , Donovan, Chantal , de Jong, Emma , Jones-Freeman, Bernadette , Ali, Md Khadem , Gomez, Henry M. , Budden, Kurtis F. , Starkey, Malcolm R. , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2022
Conditionally reprogrammed asthmatic bronchial epithelial cells express lower FOXJ1 at terminal differentiation and lower IFNs following RV-A1 infection
- Creator: Veerati, Punnam Chander , Nichol, Kristy S. , Read, Jane M. , Bartlett, Nathan W. , Wark, Peter A. B. , Knight, Darryl A. , Grainge, Christopher L. , Reid, Andrew T.
- Resource Type: journal article
- Date: 2022
IL-25 blockade augments antiviral immunity during respiratory virus infection
- Creator: Williams, Teresa C. , Loo, Su-Ling , Jackson, Crystal L. , Alton, Kirby , Shimkets, Richard A. , Girkin, Jason L. , Bartlett, Nathan W. , Nichol, Kristy S. , Reid, Andrew T. , Veerati, Punnam C. , Esneau, Camille , Wark, Peter A. B. , Grainge, Christopher L. , Knight, Darryl A. , Vincent, Thomas
- Resource Type: journal article
- Date: 2022
Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis.
- Creator: Prêle, Cecilia M. , Miles, Tylah , Rinaldi, Catherine , Laurent, Geoffrey J. , Knight, Darryl A. , Fear, Mark , Hoyne, Gerard , McAnulty, Robin J. , Mutsaers, Steven E. , Pearce, David R. , O'Donoghue, Robert J. , Grainge, Chris , Barrett, Lucy , Birnie, Kimberly , Lucas, Andrew D. , Baltic, Svetlana , Ernst, Matthias
- Resource Type: journal article
- Date: 2022
Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts
- Creator: Blokland, Kaj E. C. , Nizamoglu, Mehmet , Habibie, Habibie , Borghuis, Theo , Schuliga, Michael , Melgert, Barbro N. , Knight, Darryl A. , Brandsma, Corry-Anke , Pouwels, Simon D. , Burgess, Janette K.
- Resource Type: journal article
- Date: 2022
A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: a potential drug target in IPF
- Creator: Schuliga, Michael , Kanwal, Amama , Read, Jane , Blokland, Kaj E. C. , Burgess, Janette K. , Prele, Cecilia M. , Mutsaers, Steven E. , Grainge, Christopher , Thomson, Claire , James, Allen , Bartlett, Nathan W. , Knight, Darryl A.
- Resource Type: journal article
- Date: 2021
A senescence bystander effect in human lung fibroblasts
- Creator: Waters, David W. , Schuliga, Michael , Mutsaers, Steven E. , Grainge, Christopher L. , Knight, Darryl A. , Pathinayake, Prabuddha S. , Wei, Lan , Tan, Hui-Ying , Blokland, Kaj E. C. , Jaffar, Jade , Westall, Glen P. , Burgess, Janette K. , Prele, Cecilia M.
- Resource Type: journal article
- Date: 2021
Ageing mechanisms that contribute to tissue remodeling in lung disease
- Creator: Schuliga, Michael , Read, Jane , Knight, Darryl A.
- Resource Type: journal article
- Date: 2021
Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze
- Creator: Iosifidis, Thomas , Sutanto, Erika N. , Kicic-Starcevich, Elizabeth , Vijayasekaran, Shyan , Lannigan, Francis J. , Rigby, Paul J. , Knight, Darryl A. , Stick, Stephen M. , Kicic, Anthony , Montgomery, Samuel T. , Agudelo-Romero, Patricia , Looi, Kevin , Ling, Kak-Ming , Shaw, Nicole C. , Garratt, Luke W. , Hillas, Jessica , Martinovich, Kelly M.
- Resource Type: journal article
- Date: 2021
IL-4Ra blockade reduces influenza-associated morbidity in a murine model of allergic asthma
- Creator: Shahangian, Kimia , Ngan, David A. , Chen, H. H. Rachel , Oh, Yeni , Tam, Anthony , Wen, Jing , Cheung, Chung , Knight, Darryl A. , Dorscheid, Delbert R. , Hackett, Tillie L. , Hughes, Michael R. , McNagny, Kelly M. , Hirota, Jeremy A. , Niikura, Masahiro , Man, S. F. Paul , Sin, Don D.
- Resource Type: journal article
- Date: 2021
Inhibition of β-Catenin/CREB Binding Protein Signaling Attenuates House Dust Mite-Induced Goblet Cell Metaplasia in Mice
- Creator: Kuchibhotla, Virinchi N. S. , Starkey, Malcolm R. , Reid, Andrew T. , Heijink, Irene H. , Nawijn, Martijn C. , Hansbro, Philip M. , Knight, Darryl A.
- Resource Type: journal article
- Date: 2021
Previous influenza infection exacerbates allergen specific response and impairs airway barrier integrity in pre‐sensitized mice
- Creator: Looi, Kevin , Larcombe, Alexander N. , Perks, Kara L. , Berry, Luke J. , Zosky, Graeme R. , Rigby, Paul , Knight, Darryl A. , Kicic, Anthony , Stick, Stephen M.
- Resource Type: journal article
- Date: 2021
Regulation of cellular senescence is independent from profibrotic fibroblast-deposited ECM
- Creator: Blokland, Kaj E. C. , Habibie, Habibie , Borghuis, Theo , Teitsma, Greta J. , Schuliga, Michael , Melgert, Barbro N. , Knight, Darryl A. , Brandsma, Corry-Anke , Pouwels, Simon D. , Burgess, Janette K.
- Resource Type: journal article
- Date: 2021
Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze
- Creator: Iosifidis, Thomas , Sutanto, Erika N. , Martinovich, Kelly M. , Shaw, Nicole C. , Montgomery, Samuel T. , Kicic-Starcevich, Elizabeth , Karpievitch, Yuliya V. , Le Souëf, Peter , Laing, Ingrid A. , Vijayasekaran, Shyan , Lannigan, Francis J. , Rigby, Paul J. , Buckley, Alysia G. , Hancock, Robert E. W. , Knight, Darryl A. , Stick, Stephen M. , Kicic, Anthony , Coleman, Laura , Gill, Erin E. , Lee, Amy H. , Ling, Kak-Ming , Hillas, Jessica , Looi, Kevin , Garratt, Luke W.
- Resource Type: journal article
- Date: 2020
Airway epithelial cell immunity is delayed during rhinovirus infection in asthma and COPD
- Creator: Veerati, Punnam Chander , Troy, Niamh Mary , Reid, Andrew T. , Li, Ngan Fung , Nichol, Kristy S. , Kaur, Parwinder , Maltby, Steven , Wark, Peter A. B. , Knight, Darryl A. , Bosco, Anthony , Grainge, Chris L. , Bartlett, Nathan W.
- Resource Type: journal article
- Date: 2020
Airway epithelial-targeted nanoparticles for asthma therapy
- Creator: Kan, Stanislav , Hariyadi, Dewi Melani , Grainge, Christopher Grainge , Knight, Darryl A. , Bartlett, Nathan W. , Liang, Mingtao
- Resource Type: journal article
- Date: 2020
Airway mechanical compression: its role in asthma pathogenesis and progression
- Creator: Veerati, Punnam Chander , Mitchel, Jennifer A. , Reid, Andrew T. , Knight, Darryl A. , Bartlett, Nathan W. , Park, Jin-Ah , Grainge, Chris L.
- Resource Type: journal article
- Date: 2020
Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium
- Creator: Kicic, Anthony , de Jong, Emma , Ling, Kak-Ming , Nichol, Kristy , Anderson, Denise , Wark, Peter A. B. , Knight, Darryl A. , Bosco, Anthony , Stick, Stephen M.
- Resource Type: journal article
- Date: 2020